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br Introduction Salt stress seriously affects
2020-08-04
Introduction Salt stress seriously affects the growth and development of plants. Thus, plants have developed a variety of sophisticated strategies to respond to salt stress. To uncover these resistance mechanisms, the effects of salt stress have been studied in various species, and many genes and
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In the current study we monitored different groups at
2020-08-04
In the current study, we monitored different groups at risk for CMV reactivation. Similar to the findings from other groups, we observed CMV-reactivations with high-level viremia mostly during the first three months after alloHSCT only in the (D−/R+) and (D+/R+) group [[23], [24]]. Increasing IFN‐γ
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L-α-Aminoadipic Acid In breast cancer cell lines cell death
2020-08-04
In breast cancer cell lines, cell death induced by antiestrogen treatment [8] and inhibition by E2[9] has been reported. Like the present study, pure E2 significantly decreased the expressions of caspase-3. An inhibitory effect of E2 on caspase-3 level was also noted in the report of Somaï et al [10
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br Conflict of interest br Funding This study was
2020-08-04
Conflict of interest Funding This study was funded by the National Natural Science Foundation of China (grant number 81460027). Ethical approval Informed consent Acknowledgments Introduction Eph receptors (EphA1-8,10 and EphB1-4,6) constitute the largest family of azidothymidine s
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Recent data suggests that GRAIL
2020-08-04
Recent data suggests that GRAIL absence can lead to anti-tumor activity of CD8+ cytotoxic T cells, essential for maintenance of anti-tumor processes [60]. Rnf128 gene (encoding GRAIL ubiquitin ligase) expression was upregulated in CD8+ T Nitazoxanide infiltrated into lymphoma tumors. Additional exp
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To further explore whether it is the bisulfite
2020-08-04
To further explore whether it SR1078 is the bisulfite conversion or the HRM amplification that limited the efficiency of amplification of DNA of DNA levels below 1 ng, we performed serial dilutions of bisulfite-modified samples prepared with 1 ng of input genomic DNA. Four different quantities of DN
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br Introduction Being the fundamental unit
2020-08-04
Introduction Being the fundamental unit of life, DNA plays the vital role in long-term storage of information in the form of genetic code to instruct the cellular development and genetic propagation. The temporal profile of structural and morphological architecture of DNA provides a deep insight
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br Introduction Pattern separation is the
2020-08-04
Introduction Pattern separation is the ability to make distinct representations from highly overlapping information, a process which is important for memory encoding (Clelland et al., 2009). For correct pattern separation, old information needs to be retrieved and compared to new information. If
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We have previously shown that the brequinar
2020-08-04
We have previously shown that the brequinar-like binding mode leads to a better inhibitory activity, reflecting a high affinity binding mode. Thus, the higher activity of the compounds of the thiophene series as compared to that of the respective representatives of the cyclopentene series can easily
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Chemogenomic profiling reviewed in Nijman is another way to
2020-08-04
Chemogenomic profiling (reviewed in Nijman, 2015) is another way to identify drug MoA that have been neglected for the study of antimalarials. In a narrow sense, this approach entails perturbing the activities of different CBL0137 hydrochloride using forward or reverse genetic methods. The cell lin
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DDR AND LUNG SCCS In an exon
2020-08-03
DDR2 AND LUNG SCCS In an Fenofibrate sequencing study, Hammerman et al. identified the discoidin domain receptor 2 (DDR2) gene as a potential oncogenic target in lung SCC. The authors screened 290 tumors and cell lines and reported a 3.8% incidence of DDR2 point mutations in lung SCC samples. This
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br Experimental procedures br Results br Discussion
2020-08-03
Experimental procedures Results Discussion The results demonstrate that anti-SVG-30 produced a dose-dependent Tempol receptor in the duration of conditioned freezing, increased the level of elevated open arm exploration, and increased the amount of time spent in an open field. Hence, antag
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br CRF involvement in fear anxiety
2020-08-03
CRF involvement in fear/anxiety Given the ability of CRF and CRF1+ adenosine diphosphate synthesis to regulate BLA and CeA neuronal activity, it is unsurprising that the CRF system has also been shown to regulate fear and anxiety-like behaviors. Acute stress enhances CRF release in the amygdala (
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oxidative phosphorylation Magnified regions of the upregulat
2020-08-03
Magnified regions of the upregulated proteins identified by MALDI-TOF are shown in Fig. 2. The identified proteins were phosphoglycerate kinase, fructose-bisphosphate aldolase class II, alcohol dehydrogenase, phosphoglyceromutase, 6-phosphogluconolactonase, malate dehydrogenase, alkyl hydroperoxide
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br Acknowledgements br Introduction Bacteriophages are
2020-08-03
Acknowledgements Introduction Bacteriophages are considered as the most abundant organisms on earth that exist almost in all environments particularly where bacteria flourish, such as in wastewater and sewage [12]. One of these bacteriophages that is extensively studied is the T4 bacteriophage
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