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br Introduction Proper function of
2018-10-24
Introduction Proper function of the cerebral cortex requires the coordinated activity of two distinct neuronal populations: excitatory projection neurons and inhibitory GABAergic interneurons (cINs). In both mice and humans, roughly half of all cINs originate within the medial ganglionic eminence
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In an in vivo study the transplantation of hPSC SCP
2018-10-24
In an in vivo study, the transplantation of hPSC-SCP-SCs into a sciatic nerve-injured mouse promoted nerve fiber regeneration, and the transplanted cells integrated into renewed influenza m2 protein (Figures 5 and S6). However, without SC transplantation, demyelinated axons and nerve defects were no
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Fig b shows that the population of the upper
2018-10-24
Fig. 1b shows that the population of the upper sublevel of the 4I11/2 multiplet with the 5-Azacytidine of 2110 cm−1 does not depend on the rate of relaxation transitions relaxation to the main 4I9/2 level. The calculations proved that in order to adequately model the changes of the emission spectr
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br Assuming the curvature of the beam shape to be
2018-10-24
Assuming the curvature of the beam shape to be constant along the length of the piezoelectric actuator, we can take that where the coefficient =e31(–) is the same for all actuators, is the electrical voltage applied to the ith piezoelectric actuator. Thus, we assume that each actuator is fixed
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br Methods br Results br Discussion This
2018-10-24
Methods Results Discussion This study investigated which drug categories were responsible for the growth in fatal overdoses between 1999 and 2014 or sub-periods. Three challenges were encountered when attempting to answer this seemingly simple question. First, current death certificate data
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These results confirm that group position theory a
2018-10-24
These results confirm that group position theory, a sociological social psychological theory that explains negative emotions arising from intergroup relations, can be applied to the study of affect-related health behaviors and outcomes. In his original articulation of group position theory, Blumer a
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br Materials and methods br Results and discussion br Conclu
2018-10-24
Materials and methods Results and discussion Conclusions The centre composite design of response surface methodology was successfully used in optimising the reaction conditions for biodiesel production from waste vegetable oil in the presence of Biotin-tyramide heterogeneous catalyst prepar
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has been a remarkable year of scientific achievements from a
2018-10-23
2014 has been a remarkable year of scientific achievements, from advances in our understanding of molecular pathways of human diseases to the development of new interventional tools to tackle them. Here, we highlight some promising initiatives and success stories from the past year with clear transl
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The original premise of this
2018-10-23
The original premise of this study was that the melanoma-enriched miRNAs identified in our previous study (Stark et al., 2015) would be translated directly to the expression observed in melanoma patient-derived serum. Evidence for this notion is apparent in the serially collected stage IV melanoma p
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Vaccine studies conducted in both non human primate models A
2018-10-23
Vaccine studies conducted in both non-human primate models (Alpert et al., 2012; Gómez-Román et al., 2005; DeVico et al., 2007; Hidajat et al., 2009; Xiao et al., 2010; Brocca-Cofano et al., 2011; Barouch et al., 2012) and humans (Forthal et al., 2007; Haynes et al., 2012) have also suggested that A
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br Acknowledgments Funding for this
2018-10-23
Acknowledgments Funding for this study was obtained from the South African Medical Research Council for self-initiated research from November 2012 to April 2015 and the Lily and Ernst Hausmann Research Trust to Bongani Mayosi, and the National Institute of Allergy and Infectious Diseases of the N
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Second the uncertainty in the vector and human parameters af
2018-10-23
Second, the uncertainty in the vector and human parameters affect the value of DEP through VC and the threshold value for intensity. All six vector parameters depend on temperature. The female vector-to-human population ratio depends on temperature the same way as longevity (Brady et al., 2014). The
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The additive impact of progressive changes
2018-10-23
The additive impact of progressive changes in sleep quality and structure, changes in cerebral blood flow, neurovascular and neurotransmitters, plus the cellular redox status are all likely to contribute to the cognitive deficits reported in up to one out of four newly diagnosed OSA patients (Rosenz
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br The products of the Fanconi anemia
2018-10-23
The products of the 19 Fanconi anemia (FA) genes play important and often biochemically collaborative roles in the repair of DNA interstrand crosslinks and regulation of cellular responses to the genotoxic stress imposed by cellular replication. In response to exogenous and endogenous (e.g. aldehy
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This movement may be facilitated by the
2018-10-23
This movement may be facilitated by the formation of hydrogen bonds in the CTT as shown in Fig. 5 and Supplementary Fig. S3a. In the cGAMP-bound form, the hydrogen bonds in L374 and R375 appeared to have anchored the end of the CTT to the Lid (Fig. 5b and Supplementary Fig. S3a). L374 is especially
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