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br Acknowledgement We like to thank the Austrian Federal
2022-08-23
Acknowledgement We like to thank the Austrian Federal Ministry of Science, Research and Economy for financial support (GZ402.000/00014-WF/V/6/2016 within the Sino-Austria project) as well as Andrea Szabo and Patricia Haiss for support regarding the drawing of figures and tables. Farnesoid X Re
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On the other hand histone deacetylase inhibitors can acceler
2022-08-23
On the other hand, histone deacetylase inhibitors can accelerate inflammation resolution by promoting the externalization of AnxA1, a main ALX/FPR2 agonist, with concomitant inhibition of cytokine gene expression in mouse macrophages [30]. Thus, our present results provide an additional mechanism, i
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br Results br Discussion Immune mediated
2022-08-23
Results Discussion Immune-mediated chronic inflammatory diseases (e.g. rheumatoid arthritis, psoriasis, multiple sclerosis, and inflammatory bowel disease) are characterized by a dysregulated migration of leukocytes from blood vessels into inflamed tissues. To date, several new targets and inh
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br Conflicts of interest br Funding This work was
2022-08-23
Conflicts of interest Funding This work was supported by the Higher Education Commission Pakistan start-up research grant to Anjum Riaz. Introduction Distraction osteogenesis (DO) is an endogenous tissue engineering technology used to repair skeletal including craniofacial deformities, in
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Literature review suggests a strong presence of central
2022-08-22
Literature review suggests a strong presence of central histaminergic transmission in the trpv1 antagonist areas targeted by caffeine to induce its behavioral actions. Interestingly, it is reported that caffeine administration increases the histamine neuronal activation and release of histamine in
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br Materials and methods br Results We examined the
2022-08-22
Materials and methods Results We examined the cardiac mitochondrial density of HKI and markers of oxidative and metabolic stress in trout exposed to an aerated control exposure, an aerated (normoxic) thermal insult, or a hyperoxic thermal insult. Should mtHK provide a cardioprotective effect i
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br Introduction Adipose tissue AT in addition to
2022-08-22
Introduction Adipose tissue (AT), in addition to its function as Tunicamycin storage, is an important endocrine organ and it secretes adipokines (Ahima, 2006). Adipose tissue is related to different physiological processes such as energy metabolism, insulin sensitivity, and inflammation. One impo
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The average pregnancy rate in this work was similar results
2022-08-22
The average pregnancy rate in this work was 60.1%; similar results have been reported with the same estrus synchronization treatment (58% pregnancy rate) [26]. Later studies also showed that the pregnancy rate was 56.9 and 51.1%, with FTAI and estrous detection, respectively [34,35]. Although that t
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Based on the molecular weights
2022-08-22
Based on the molecular weights of glutamate (147.13 g/mol) and MSG (169.111 g/mol), the amount of free glutamate intake obtained in this study was equivalent to 297 mg MSG/d and 370 mg MSG/d for children and adults, respectively. Several previous studies have assessed population intake of MSG from f
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Having shown that some of substitutions Cl
2022-08-22
Having shown that some of substitutions (Cl, CF) at the 2-position of the thiophene improved rat microsomal stability, and polar groups at the 4-position of the aryl ring had a beneficial effect on stability in both human and rat microsomes, we combined these features in a new set of analogs. Methyl
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Nuclear export of GK has been reported to
2022-08-22
Nuclear export of GK has been reported to be dependent on a GK nuclear export signal (NES), mapped to residues 300–310 (Shiota et al., 1999). The assignment of a nuclear export signal common to both the liver and pancreatic GK isoform sequence suggests a possible reversible translocation of GK acros
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br Acknowledgments We apologize to the researchers who were
2022-08-19
Acknowledgments We apologize to the researchers who were not referenced due to space limitations. We thank Christine Heiner (Department of Surgery, University of Pittsburgh) for her critical reading of the manuscript. This work was supported by grants from the US National Institutes of Health (R0
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br Site of expression FASTK is
2022-08-19
Site of expression FASTK is expressed in various parts of human body including heart, skeletal muscle, brain, placenta, lung, liver, kidney pancreas (Ota et al., 2004) and many other organs (Fig. 1). It has been reported that FASTK is highly expressed in pancreatic tumors, where it is involved in
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br Materials and methods All studies were performed in
2022-08-19
Materials and methods All studies were performed in 230–250g timed-pregnant Sprague Dawley rats (Harlan, Indianapolis, Indiana). Animals were housed in a temperature controlled room with a 12:12 light:dark cycle. All experimental procedures in this study were in accordance with the National Insti
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Recently the classical view of the compartmentalization
2022-08-19
Recently, the classical view of the compartmentalization of the plant isoprenoid metabolism has been re-evaluated, following the demonstration of the partial peroxisomal localization of the mevalonic Nalidixic acid (MVA) pathway, generally regarded as cytosolic. Using GFP-tagging approaches, the la
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