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Rice approximately covers of land area
2020-11-26

Rice approximately covers 1% of land area of the earth and it is one of the main sources of food for billions of people [4]. One of the main agriculture industry residues is rice husk, which contains high amount of amorphous silica up to 85–95%. Rice husk ash (RHA) is a solid residue of rice husk co
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Some authors rather than using magnetic
2020-11-25

Some authors, rather than using magnetic NPs as heat sources, have enhanced the activity of the linked enzymes by applying low frequency AMF. Magnetic energy is converted into a rotational motion of the enzyme-particle system that increase the collision rate with the substrate [14], [15], or trigger
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The role of ETB clearing receptors has been studied in
2020-11-25

The role of ETB clearing receptors has been studied in detail in endothelial cell–specific ETB knock-out mice. In these animals, clearance of an intravenous PRT062070 synthesis of labeled ET-1 was reduced significantly compared with wild-type controls. Importantly, functioning ETB were retained on
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br Regulation of cadherin switching
2020-11-25

Regulation of cadherin switching The downregulation of E-cadherin during cadherin switching is induced by multiple mechanisms, including methylation of the E-cadherin promoter and signaling pathways that activate E-cadherin-suppressing transcription factors [[61], [62], [63]]. During the progress
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br Lymphoplasmacytic lymphoma Waldenstrom macroglobulinemia
2020-11-25

Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia Lymphoplasmacytic lymphoma (LPL) and its subgroup Waldenstrom macroglobulinemia (WM) are rare and indolent lymphomas that arise from fully differentiated B cells. The only family of GPCRs that has been well studied in LPL/WM is the chemokin
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A key inciting event in atherosclerosis is the deposition
2020-11-25

A key inciting event in atherosclerosis is the deposition of circulating low-density lipoprotein (LDL) in the subendothelial space of major arteries. In the subendothelium, native LDL is no longer protected by circulating antioxidants and is oxidatively modified to oxidized LDL (OxLDL) [5]. OxLDL is
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Crystallographic and NMR based analyses have revealed that
2020-11-25

Crystallographic and NMR-based analyses have revealed that RINGs and U-boxes have a common mode of interaction with E2s (Fig. 2A). The key structural elements are two loop-like regions, which, in the case of RINGs, coordinate Zn. The loops surround a shallow groove formed by the central α-helix. Tog
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Introduction DHFR is an important enzyme in both mammals
2020-11-25

Introduction DHFR is an important enzyme in both mammals and microorganism including Mycobacterium tuberculosis (Mtb). It catalyzes folic TC-I 2000 mg conversion to dihydro and tetrahydro folic acid which is a crucial step in folate pathway [1]. Inhibition of folate pathway leads to interruption o
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Reports on the participation of NDH along with other
2020-11-25

Reports on the participation of NDH2 along with other respiratory complexes in the formation of a large supercomplex (Grandier-Vazeille et al. 2001) or even a respirosome-like structure in S. cerevisiae mitochondria (Matus-Ortega et al. 2015) are very intriguing. Similarly, in Y. lypolytica mitochon
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br The contribution of Interference RNA and
2020-11-25

The contribution of Interference RNA and epigenetic in OA attenuation Interference RNA, a cellular mechanism for post-transcriptional gene silencing that is associated with mRNA. The potential of RNAi has successfully silenced the wide range of protein coding genes. Its high specificity sanctions
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Although the crystal structures of Atg C
2020-11-25

Although the crystal structures of Atg4C and Atg4D are not available, their three dimensional structures can be acquired by homology modeling, using the structure of Atg4B as a template (Zhang, Li, Ouyang, Liu, & Cheng, 2016). In that model, the catalytic triad is conserved (Cys110/Asp345/His347 for
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Compound was generated using a literature procedure and requ
2020-11-25

Compound was generated using a literature procedure and required two-step Dess–Martin-periodinane/Pinnick oxidation prior to the methylation of the sulfonamide. Compound () was obtained from the Suzuki coupling of the methyl ester intermediate (en route to L-Arabinose ). Hydrolysis of all methyl est
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Previous studies reported that NE and MHPG are deeply involv
2020-11-24

Previous studies reported that NE and MHPG are deeply involved in depression and that NE reuptake inhibitors are approved for use in patients with depression (for review, see [2]). We found increased hippocampal content of NE and MHPG in the CORT-treated CRTH2−/− mice (Fig. 3). In the hippocampus, a
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Sixty eight male Sprague Dawley rats were
2020-11-24

Sixty-eight male Sprague–Dawley rats were acquired from the University of South Dakota Laboratory Animal Services (Vermillion, SD, USA) and housed in pairs at 22°C (60% relative humidity) on reverse 12h light/dark WZ4003 (dark cycle started at 10:00a.m.) with food and water freely accessible. The p
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anderson kpt Finally the recent work to define
2020-11-24

Finally, the recent work to define the microcircuitry of the central amygdala and the role of specific cell populations in fear conditioning can stand as a useful model for advances in preclinical alcohol research. To date, the role of the amygdala in alcohol-related behaviors, and reward-related be
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