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En la interiorizaci n del
2018-10-25
En la interiorización del desprecio antes mencionada, también se interioriza un lenguaje y una forma de hablar de sí mismo, los cuales serán el ancla para las prácticas de sí. Por eso, para Monsiváis es tan importante que los sujetos puedan hablar sobre sí mismos. Solo en ese interregno entre la exp
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Introducci n Desde hace algunos a os la interseccionalidad s
2018-10-25
Introducción Desde hace algunos años, la interseccionalidad se ha convertido en la expresión utilizada para designar la perspectiva teórica y metodológica que busca dar cuenta de la percepción cruzada o imbricada de las relaciones de poder. Este enfoque no es novedoso dentro del feminismo y, de hec
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The protection of Carrageenan induced
2018-10-25
The % protection of Carrageenan induced paw edema in rat was treated with phenylbutazone guggulosomes. The rats were treated with optimized formulation F3 of prepared guggulosomes. The controlled and treated rats were observed for 0.5, 1, 2, 3 & 4 h on plethysmometer and anti-inflammatory effect was
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br The ethics of cell
2018-10-24
The ethics of cell therapy Clearly then, cell therapy and regenerative medicine in general raise a number of ethical, economical and regulatory issues that were addressed in an ad hoc session. As a general introduction to this very complex landscape, John Harris (University of Manchester) took le
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The dynamic clonal behavior and conversion of
2018-10-24
The dynamic clonal behavior and conversion of leukemic tolterodine tartrate that we observed in our mouse model show resemblance with patients presenting with leukemic relapse after treatment. First, if remissions in relapsed patients are treated similarly as the original leukemia, the response is
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br Experimental Procedures br Acknowledgments br Introductio
2018-10-24
Experimental Procedures Acknowledgments Introduction Master transcription regulators control the pluripotent gene expression in embryonic stem prostaglandin receptor (ESCs) (Avilion et al., 2003; Chambers et al., 2003; Mitsui et al., 2003; Nichols et al., 1998). X chromosome inactivation (
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However before application in a clinical
2018-10-24
However before application in a clinical context, a number of issues still need to be considered. Indeed, SSC transplantation in cancer patients requires techniques to exclude cancer cell contamination, because implantation of as few as 20 leukemic direct thrombin inhibitors can result in cancer re
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br Materials and Methods br Results
2018-10-24
Materials and Methods Results Discussion The importance of bone marrow microenvironment in leukemogenesis becomes more evident each day. Kim and colleagues described the ability of leukemic stem pramiracetam to reset the communication between hematopoietic stem cells and the bone marrow mi
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Introduction Glioblastoma multiforme GBM is the most common
2018-10-24
Introduction Glioblastoma multiforme (GBM) is the most common adult primary orexin a tumor, with an extremely dismal prognosis and high rate of recurrence following standard therapy (Wen and Kesari, 2008). Populations of brain tumor initiating cells (BTICs), which express many of the properties of
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WNT signaling is well recognized for its role
2018-10-24
WNT signaling is well recognized for its role in regulating stem and progenitor buy stavudine in diverse systems (Nusse et al., 2008). Elevated levels of β-catenin, indicative of aberrant WNT signaling, are reported in more than 50% of human breast carcinomas, correlate with poor prognosis, and are
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The reprogramming of somatic cells was originally demonstrat
2018-10-24
The reprogramming of somatic GPCR Compound Library was originally demonstrated by producing cloned frogs using somatic cell nuclear transfer (SCNT) into Xenopus oocytes (Gurdon et al., 1958). Reprogramming of mammalian somatic cells has also been achieved using SCNT into oocytes, including those of
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br Results br Discussion We report on
2018-10-24
Results Discussion We report on the derivation and full characterization of two hESC lines (SZ-ALS1 and SZ-ALS3) with a GGGGCC expansion of approximately 270 repeats. Our C9 hESC lines were established from embryos obtained through PGD from a woman with a C9 mutation with >40 repeats in her pe
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We assessed levels of cell death
2018-10-24
We assessed levels of cell death using annexin V and propidium iodide staining. The tp53 animals showed a 20% increase in erythroid cell death when assessed by propidium iodide staining (p = 0.02, Figures 4A and S3A), but no increase in annexin V staining (Figures S3A and S3B), similar to what was o
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To study the cellular and molecular events
2018-10-24
To study the cellular and molecular events of FTD3, we derived a disease model using human iPSCs from patients carrying the 31449G > C mutation in CHMP2B and isogenic controls generated via the CRISPR/Cas9 system with subsequent in vitro neuronal differentiation. Our model not only confirmed partly
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br Results Disease modeling using iPSCs can be
2018-10-24
Results Disease modeling using iPSCs can be confounded by phenotypic variation resulting from genetic differences between individual iPSC lines (Merkle and Eggan, 2013). To overcome this obstacle, we sought to generate isogenic cell lines by targeted correction of the point mutation in the SOD1 i
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